Light rail runs that way if you don't want to rent a car.
The recently opened W-line on the Light Rail runs to and from downtown Denver with a transfer at Union station taking you to DIA. It's the most cost-effective form of transportation provided you have the time to spare. The hotel itself also has a town car service reservable for a flat fee. Other than that, SuperShuttle, Yellow Cab, Metro Taxi, Uber, Lyft, or similar rideshare options will all take you to directly to or from DIA, but at a much more expense to you.
Rental car is the fastest and most convenient way to get the hotel
Thanks! Your answer is awaiting moderation.