Yes as long as you are either local or have a round trip ticket, most car rental places will take a debit card. The thing to remember is that Enterprise will put a hold on whatever card you use, debit or credit, for $250 or rental amount plus $150 whichever is greater. When using a regular credit card the excess usually goes back on the card 2 business days after the car is returned. When using a debit card it is a little more difficult to pinpoint the return of funds. It can take up to 21 business days depending on how your bank works.
I'm not sure I would call them the problem with a debit card is the hold and the amount is high like a deposit
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