Unfortunately no, the closest one to the Depot is Enterprise Rent-A-Car but they close at 6 p.m. If you go to the airport (via Uber or Cab) there are several car rental companies open until the a.m.
Avis car rental at 5th and Bst is the closest or Enterprise on 5th and Ingra also between 4th and 5th on Kst
Thanks! Your answer is awaiting moderation.