Are things priced higher at this downtown Target vs. other locations? And do they sell cleaning supplies?

I would say no..prices are the same as other Target locations. Yes they do sell cleaning supplies.

I think the tax rate is higher but the price is the same you would pay at any other Target store.

I think most things at Target tend to be priced the same everywhere with few exceptions. Alaska and Hawaii being exceptions of course.

Agreed, good offering of cleaning products and same pricing as other stores locally.