There is a Ronald McDonald House located near Hollings Cancer Center for families of children 18 years of age or younger who are receiving inpatient or outpatient medical treatment in the Charleston area. More information may be found here: https://www.rmhcharleston.org/stay-with-us/
Hope lodge is available but needs to be set up by your social worker. And there are hotels and other lodging that offer discounts if setup by the concierge in the lobby.
Not right Across the street Several places close by Call Holland's Center make reservation and they will set you up with the closest spot
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