Is it possible to hike NC and Maryland without camping? I can no longer carry the weight needed to have tent, stove, sleeping bag, etc. is there lodging to do a series of day hikes?

We did it with friends. Two cars. Exchange keys and stay motels. Did this for 1,800 miles. Not in the Smokies or 100 mile wilderness

No there is not unfortunately. However, if you do some figuring and have a friend or family member in the area, I'm sure you can set up a slack packing sort of thing where you have your friend/family member carry some of your gear in their car to set up points where you would meet them.

No