I've been fortunate and been allowed to stay at Hope Lodge on and off since 2014. Fantastic place, fantastic staff!!! If you're staying at Hope Lodge, you don't need a car for anything: there are shuttles to hospitals, and subway, trains and busses are virtually just outside the door. If you need a car to get there, find somewhere cheap to park, somewhere outside the city center, and leave your car there for the entire stay. Better still: if you're going to stay for some time, get there by public transport and rent a car in the city to get out and away whenever you need to...
Should be able to park in garage near by. Expensive.
Oi! Parking in NYC is always a nightmare or a nightmare plus expensive! Perhaps Hope Lodge can help you with this question. Sorry I can't help more and Best wishes.
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