Hello, Can you replace an outdoor glass insert to a table that has a hole in the center for an umbrella. Purchased at Lowes.

It can be done. It depends if you want actual glass or a polycarbonate equivalent. The polycarbonate should be much quicker to get, as it can usually be taken care of in-house, usually on the same day. If you want tempered glass with a hole, typically it can take a week or more to get it as it has to be special ordered to size and with the proper size and location of umbrella hole.

It depends on some details but probably yes.