I would say the neighborhood isn't the worst for NYC, and regardless, the garment district really is the place to go for any fabric or fashion related materials. People might be a little confused nearby since a lot of tourists pass through going to either Broadway or times square right next door and consequently some people are haggling for change and whatnot but nothing ridiculous. I'd also say that AK fabric is a mixed bag in terms of quality, it's really good for the price and it beats out small town fabric stores but mood is an all time for a reason, it's overpriced sure but it's hard to find comparable quality if you're after that. You'll be safe though, and if you take the train, 42nd Street port authority station is calmer than 32nd Street.
The neighborhood is fine. Lots of commuters walk through it everyday so lots of foot traffic especially around rush hour.
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