Unfortunately not; there is a " Coaster" that runs from downtown San Diego to Oceanside but not to Escondido Ca.
Well, if you just want your trip from San Ysidro to Escondido to traverse nothing but railway lines you can transfer in downtown SD to the aforementioned Coaster (which is a real train, passenger coaches pulled by a diesel engine) and in Oceanside transfer to the "Sprinter," which is like a bus that runs on a railroad track. Would take forever, tho; best bet is to catch the trolley to the City College station and transfer to Bus #235 - about an hour and a half trip one way.
ok thanks
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