I have a schedule appointment on may17,2019 but it show office is closed and i live in juneau what should i do i have no way of calling the number nobody answer

USCIS knows you have an appointment with them, regardless if it says it's close or nobody's answering your call. Just go to your scheduled appointment. Trust me, they'll be there.

In must cases, there is a number 1800 in your appointment letter take a video of office closed or contact Anchorage office, for reschedule your appointment.