Yes, but like Randy said not all may be open. There is a shuttle bus 24/7 right outside of baggage pic up. That shuttle takes you to the car rental place that has all the providers. You can also call the rental providers at sea tac, for instance enterprise maybe one, and talk to them and get answer...or do it on your smart phone or computer. You have lots of options. Hope that helps
Not all of the agencies are open. However, if you reserve in advance, you should be able to use the kiosks to check in and get a car. I would recommend Enterprise because I know they offer that service.
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