Yea just call the airline
Check with airline. I think as long as there is someone to take them at gate and to pick them up at gate. Each airline has different rules. Check out Southwest's policy: unaccompanied_minors_terms_and_conditions_faq.html
The airline staff takes care of children flying alone. When making reservations, I'd recommend calling the airline service that you are flying them with.
You can ask to the airline I am sure they will help you
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