There are plenty of hotels within a block or two of 16th st with varying prices. One that's right for you will depend on how much you want to spend.
Idk of a specific one on 16th st. But there's a few by the mall. The hyatt has a bar on the 24th floor if im not mistaking.. The ritz carlton is there.
There are many clean nice hotels
Westin is close by and clean
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