Fares are lower in the mid week & booked ahead-having 6:am departure problems from Roanoke lately & resently a one way 26 hr screw to Ny.
You have to check the Greyhound website due to the fact the fares are different for for different destinations and change everyday. However they are usually lower on Tuesday and Wednesday and get more expensive the closer to the time you plan to leave so try to book as far in advance as you can.
Greyhound had a web site with specific answers the fairs are usually different and higher on the weekends
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