I would recommend getting a Lyft or an Uber. It's difficult to park down there; however, the closest parking is probably the Monteleone garage. Street parking is available in the surrounding blocks, but it is hard to come by and there are tricky no parking zones for the hotels, etc.
Parking is difficult at the French Quarter unless you are staying at a hotel within the neighborhood. Uber is one of the easiest ways to avoid concerns over parking.
If you live in NOLA I would recommend an Uber etc... There is a parking lot at 316 Chartres.
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