4or 5 months
She has to weigh a certain amount, I believe it's 2 lbs. which a lab puppy certainly does. The dog can be spayed while a puppy. For males, it is better to wait a little later for health and development. Spaying or neutering is the most important thing you can do for your dog, second only to proper training and socialization. Getting enrolled in puppy training will allow you to learn about development, to head off bad habits and create a wonderful lifelong relationship.
As far as I know the animals must be at least 4 months or before their first heat.
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