Does Manning's Sports Bar take reservations?

Yes

I'm sure but you really don't need them at this time. Would not recommend it at this time. Not sure if it's a limited menu or is that an everyday menu but it sucks (not enough variety)

We went Friday night and no reservation was needed. It was dead. They are limiting their hours way too much and people apparently aren't bothering to go. We went because it was close to our hotel and they closed at 10pm on a Friday night. Not very New Orleans.