5 or a couple of minutes after
We had no TSA delays at all this week, never waited more than a minute.
I would imagine 4:45am would be fine (for a 6am flight)...assuming boarding begins @ 5:30am.
I've never had TSA take any longer than 30 minutes here. So an hour to be safe. My most recent flight was late November 2018
I'd give it two hours if possible. I believe security opens around 4:30am, but check the TSA website.
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