Can tickets be bought at the location?

Yes

Yes they can! We just went last weekend. For $30 a person you get access to both Lucy/Lucy Desi museums AND the Comedy museum a few blocks away. The comedy museum is great too! All hands on. They give you your own personal set of headphones and a stylis to keep so you don't have to touch things. The displays that you do have to touch have boxes of disposable gloves and hand sanitizer next to them. It's worth the trip and the money!!