Why is it so hard to figure out this site? I wanted I formation on regular routes if any from Charleston to Columbia and can't seem to navigate to that information.

Lol, no i was trying to figure out amtrak routes but i appreciate the quick response. I was on the amtrak site and thought the community thing was in reference to thst. Sorry.

Only one route really and thats the dreadful I-26. Unless you're up for a nice scenic and historical route Highway 61 will take you through the Plantation district with its canopy oaks. 52 is also an option but at some point both of those routes will require you to migrate back toward Columbia since they both move slowly west and east of Columbia if you stay on them.