Can you take a greyhound bus from anderson ,s.c. to kingstree,s.c.

Yez

That question is beyond my scope. The 800 number should be able to assist you, but the computer is not recognizing the city you are traveling to.

I am not sure

I am not too sure. You will have to look on Greyhounds website to check their routes and schedule times. Hopefully this helps you out.