Can I pick up at airport and drop off at a different Enterprise location? Maybe Canal Street?

I would call first. I have done it but there was a charge associated with dropping off at a different location.

I've had the experience of picking up a car at the airport and dropping off at a different location a couple times with Enterprise. They seem to have a 'fluid' relationship with each other throughout the company. I have been able to arrange this online ... But they are also available by telephone if having troubles figuring this out.