Would you recommend Disney Hollywood Studios over Universal for a 5 and 10 year old? Why?

Thats a very personal appreciation and may be different for two children of 5 years old and two children of 10 years old.

I've never been to universal studios. I've only been to Hollywood studios. I would probably recommend universal unless your children are huge star wars fans. Hollywood studios is mostly dedicated to Star wars. So unless you're children are MASSIVE star wars fans, they would probably get more out of universal studios