In general, higher wager slots have a higher chance to win. Higher wager meaning dollar slots vs penny slots. Therefore, a $1 wager at 3 credits ($3 bet) would have increased odds compared to a $0.01 wager at 420 credits ($4.20 bet). That being said, it's a very small increased chance, so the odds are still in the casino's favor.
In my opinion, no.
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